| CAMPSQ773 |
| Title : |
Dybowskin-3 , Brevinin-2DYc |
| GenInfo Identifier : |
160380517 |
| Source : |
Rana dybowskii [Dybovsky frog] |
| Taxonomy : |
Animalia, Amphibia |
| UniProt: |
P0C5X3 |
| PubMed : |
17698251 , 17688900 |
| Activity : |
Antibacterial, Antifungal |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
M. luteus ( MIC = 6.25 microg/ml ), Staphylococcus aureus ( MIC = 30 microg/ml ), Bacillus subtilis ( MIC = 50 microg/ml ), Staphylococcus epidermidis ( MIC = 60 microg/ml ), Shigella dysenteriae ( MIC = 60 microg/ml ), Escherichia coli ( MIC = 15 microg/ml ), Klebsiella pneumoniae ( MIC = 15 microg/ml ), Proteus mirabilis ( MIC = >100 microg/ml ), Pseudomonas aeruginosa ( MIC = >100 microg/ml ), Candida albicans ( MIC = 100 microg/ml ) |
| Hemolytic Activity : |
hRBC (1.86% hemolysis at 100 microg/ml) |
| Validated : |
Experimentally validated |
| Pfam : |
PF08023 : Antimicrobial_2 ( Frog antimicrobial peptide )
|
| InterPro : |
IPR012521 : Antimicrobial_frog_2.
|
| AMP Family : |
Brevinin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
BrevininH33_60 |
HMM |
 |
|
RanateurinH32_9 |
HMM |
|
|
BrevininH_224 |
HMM |
|
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
|
| Length : |
33 |
Sequence: |
GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC |
