CAMPSQ699
Title : Nigrosin-OG20 , nigrocin-2GRa , Grahamin-1, nigrosin-OG17, Grahamin-2
GenInfo Identifier : 110560345
Source : Odorrana grahami [Yunnanfu frog]
Taxonomy : Animalia, Amphibia
UniProt: A6MBA3 , P0C2A4, P85070
PubMed : 17272268 , 16621155 , 16487561
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
[ Refer PubMed 17272268 : - E. coli ( MIC = >100 microg/ml), S. aureus ( MIC = 75.00 microg/ml), B. subtilis ( MIC = 9.37 microg/ml), C.albicans ( MIC = 9.37 microg/ml) ] [ Refer PubMed 16621155 :- E. coli ( MIC = 25 microM), S. aureus ( MIC > 100 microM)
Hemolytic Activity :
Hemolytic activity ( LC50 = 295 microM)
Validated : Experimentally validated
Pfam : PF16047: Antimicrobial22
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR004275 : Brevinin.
AMP Family : Nigrocin
Signature :
ID Type Pattern / HMM
NigrocinH21_35 HMM
NigrocinH_39 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0050829 Biological process Defense response to Gram-negative bacterium IEA
GO:0050830 Biological process Defense response to Gram-positive bacterium IEA
GO:0006955 Biological process Immune response IEA
GO:0005576 Cellular component Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
GO:0005576 Biological process Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
Length : 21
Sequence:
 GLLSGILGAGKNIVCGLSGLC

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