CAMPSQ687
Title : Cathelicidin-5 , Antibacterial peptide BMAP-28 , Myeloid antibacterial peptide 28
GenInfo Identifier : 1708946
Source : Bos taurus [Bovine]
Taxonomy : Animalia, Mammals
UniProt: P54229
PubMed : 8910461, 29103679
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
E. coli ATCC 25922 ( MIC = 2 microM), E. coli ML35 ( MIC = 2 microM), E. coli D21 ( MIC = 0.5 microM), S. typhimurium ATCC 14028 ( MIC = 1 microM), P. aeruginosa ATCC 27853 ( MIC = 1 microM), S. marcescens ATCC 8100 ( MIC = 2 microM), S. aureus ATCC 25923 ( MIC = 2 microM), S. aureus Cowan 1 ( MIC = 1 microM), S. aureus ( MIC = MRSA microM) ( MIC = 4 microM), S. epidermidis ATCC 12228 ( MIC = 1 microM), B. megaterium Bm11 ( MIC = 2 microM), C. albicans ( MIC = 8 microM), C. neoformans ( MIC = 4 microM) [Refer PubMed ID: 29103679] S. aureus (LOG 2MIC =4.35), E.coli(LOG 2MIC=5.80)
Validated : Experimentally validated
InterPro : IPR001894 : Cathelicidin.
IPR001894 :
IPR018216 : Cathelicidin_CS.
IPR018216 :
AMP Family : Cathelicidin
Signature :
ID Type Pattern / HMM
CathelicidinH28_2 HMM
CathelicidinH_140 HMM
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
GO:0005615 Cellular component Extracellular space IBA
GO:0001530 Molecular function Lipopolysaccharide binding IBA
GO:0061844 Biological process Antimicrobial humoral immune response mediated by antimicrobial peptide IBA
GO:0050829 Biological process Defense response to Gram-negative bacterium IBA
GO:0050830 Biological process Defense response to Gram-positive bacterium IBA
GO:0045087 Biological process Innate immune response IBA
Length : 28
Sequence:
 GGLRSLGRKILRAWKKYGPIIVPIIRIG

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