CAMPSQ538
Title : Adenoregulin
GenInfo Identifier : 585056, 260423
Source : Phyllomedusa bicolor [Two-colored leaf frog]
Taxonomy : Animalia, Amphibia
UniProt: P31107
PubMed : 8306981
Activity : Antibacterial, Antifungal
Gram Nature : Gram -ve
Target :
Microsporum canis IP 11 94 ( MIC = 10 microg/ml), Tricophyton rubrum IP 1400-82 ( MIC = 15 microg/ml), Arthroderma simii IP 1063-74 ( MIC = 30 microg/ml), Aspergillus fumigatus IP 1025-70 ( MIC = 125 microg/ml), Aerornonas caviae IP 67-16 T ( MIC = 60 microg/ml), Escherichia coli IP 76-24 ( MIC = 15 microg/ml), Nocardia brasiliensis IP 16-80 ( MIC = 30 microg/ml), Cryptococcus neoformans IP 960-67 ( MIC = 15 microg/ml), Cryptococcus neofonnans IP 962-67 ( MIC = 15 microg/ml), Candida albicans IP 884-65 ( MIC = 15 microg/ml).
Validated : Experimentally validated
Pfam : PF12121 : DD_K ( Dermaseptin )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR004275 : Brevinin.
IPR022731 : Dermaseptin.
AMP Family : Dermaseptin
Signature :
ID Type Pattern / HMM
DermaseptinH33_3 HMM
DermaseptinH_57 HMM
DermaseptinP33_3 Pattern G-L-W-S-K-I-K-[AET]-[AV]-G-K-E-A-A-K-A-A-A-K-A-A-G-K-A-A-L-[GN]-A-V-S-E-A-[IV]
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0016020 Cellular component Membrane IEA
GO:0005085 Molecular function Guanyl-nucleotide exchange factor activity IDA
GO:0050832 Biological process Defense response to fungus IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of other organism IEA
GO:0005576 Cellular component Extracellular region IDA
GO:0016020 Cellular component Membrane IEA
GO:0044218 Cellular component Other organism cell membrane IEA
GO:0005085 Molecular function Guanyl-nucleotide exchange factor activity IDA
GO:0050832 Biological process Defense response to fungus IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0045087 Biological process Innate immune response IEA
GO:0031640 Biological process Killing of cells of another organism IEA
Length : 33
Sequence:
 GLWSKIKEVGKEAAKAAAKAAGKAALGAVSEAV

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