CAMPSQ459
Title : Esculentin-1
GenInfo Identifier : 416969
Source : Rana esculenta [Edible frog]
Taxonomy : Animalia, Amphibia
UniProt: P32414
PubMed : 8508915
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
E.coliD21 ( MIC = 0.2 microM), B. megaterrum Bm11 ( MIC = 0.1 microM), S.aureus Cowan1 ( MIC = 0.4 microM), P.aeruginosaATCC15692 ( MIC = 0.7 microM), C.albicans ( MIC = 0.5 microM), S. cerevisiae ( MIC = 0.9 microM)
Hemolytic Activity :
Red blood cells (>100 microM)
Validated : Experimentally validated
Pfam : PF08023 : Antimicrobial_2 ( Frog antimicrobial peptide )
InterPro : IPR012521 : Antimicrobial_frog_2.
AMP Family : Esculentin
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IDA
GO:0050829 Biological process Defense response to Gram-negative bacterium IDA
GO:0050830 Biological process Defense response to Gram-positive bacterium IDA
GO:0044179 Biological process Hemolysis in other organism IDA
Length : 46
Sequence:
GIFSKLGRKKIKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC

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