| CAMPSQ4143 |
| Title : |
Brevinin-1JDa |
| GenInfo Identifier : |
410591617 |
| Source : |
Odorrana jingdongensis [Jingdong frog] |
| Taxonomy : |
Animalia, Amphibia |
| UniProt: |
B3A0M4 |
| PubMed : |
22917879 |
| Activity : |
Antibacterial |
| Gram Nature : |
Gram +ve, Gram -ve |
| Target : |
Staphylococcus aureus (ATCC 25923) ( MIC= 16 microg/ml ), Methicillin-resistant S. aureus (MRSA, CIB 85462) ( MIC= 32 microg/ml ), Escherichia coli (ATCC 25922) ( MIC= 128 microg/ml ), Extended-spectrum-lactamases E. coli (ESBL, CIB 84492) ( MIC= 64 microg/ml), Candida albicans ( MIC = 128microg/ml) |
| Hemolytic Activity : |
Rabbit erythrocytes 79.2±6.8% lysis (128 microg/ml) |
| Validated : |
Experimentally validated |
| Pfam : |
PF08018 : Antimicrobial_1 ( Frog antimicrobial peptide )
|
| InterPro : |
IPR012520 : Antimicrobial_frog_1.
|
| AMP Family : |
Brevinin |
| Signature : |
| ID |
Type |
Pattern / HMM |
|
BrevininH24_87 |
HMM |
 |
|
BrevininH_224 |
HMM |
|
|
| Gene Ontology : |
| GO ID |
Ontology |
Definition |
Evidence |
| GO:0005576 |
Cellular component |
Extracellular region |
IEA |
| GO:0042742 |
Biological process |
Defense response to bacterium |
IEA |
| GO:0050832 |
Biological process |
Defense response to fungus |
IEA |
| GO:0044179 |
Biological process |
Hemolysis in other organism |
IEA |
|
| Length : |
24 |
Sequence: |
FLPAVIRVAANVLPTVFCAISKKC |
