CAMPSQ239
Title : Gomesin
GenInfo Identifier : 20664097
Source : Acanthoscurria gomesiana [Tarantula spider]
Taxonomy : Animalia, Arachnida
UniProt: P82358
PDB: 1KFP
Structure Database : CAMPST31
PubMed : 10942757, 28741926
Activity : Antibacterial, Antifungal
Gram Nature : Gram +ve, Gram -ve
Target :
Refer PubMed ID 10942757: Aerococcus viridans ( MIC = 0.8-1.6 microM), Bacillus cereus ( MIC = 6.25-12.5 microM), Bacillus megaterium ( MIC = 0.2-0.4 microM), Bacillus thuringiensis ( MIC = 1.6-3.15 microM), Enterococcus faecalis ( MIC = 6.2-12.5), Listeria monocytogenes ( MIC = 0.8-1.6), Micrococcus luteus ( MIC = 0.4-0.8 microM), Pediococcus acidolacrici ( MIC = 3.15-6.25 microM), Staphylococcus aureus ( MIC = 1.6-3.15 microM), Staphylococcus epidermidis ( MIC = 0.8-1.6 microM), Staphylococcus haemolyticus ( MIC = 0.8-1.6 microM), Staphylococcus saprophyticus ( MIC = 0.8-1.6 microM), Streptococcus pyogenes ( MIC = 1.6-3.15 microM), Nocardia asteroides ( MIC = 1.6-3.15 microM), Alcaligenes faecalis ( MIC = >100 microM), Escherichia coli 1106 ( MIC = 0.8-1.6 microM), Escherichia coli D22 ( MIC = 0.4-0.8 microM), Escherichia coli D31 ( MIC = 0.8-1.6 microM), Escherichia coli SBS363 ( MIC = 0.4-0.8 microM), Erwinia carolovora carolovora ( MIC = 3.15-6.25 microM), Enterobacter cloacae beta 12 ( MIC = 3.15-6.25 microM), Klebsiella pneumoniae ( MIC = 3.15-6.25 microM), Pseudomonas aeruginosa ( MIC = 1.6-3.15 microg/ml), Salmonella typhimurium ( MIC = 0.8-1.6 microM), Xhantomonas campestris pv. orizae ( MIC = 3.15-6.25 microM), Alternaria brassicola ( MIC = 0.4-0.8 microM), Aspergillus fumigatus ( MIC = 1.6-3.15 microM), Beauveria bassiana ( MIC = 12.5-25 microM), Fusarium culmorum ( MIC = 0.4-0.8 microM), Fusarium oxysporum ( MIC = 0.4-0.8 microM), Neurospora crassa ( MIC = 0.4-0.8 microM), Nectria haematococca ( MIC = 0.2-0.4 microM), Tricoderma viridae ( MIC = 0.4-0.8 microM), Tricophvton mentagrophytes ( MIC = 0.8-1.6 microM), Candida albicans ( MIC = 0.15-0.3 microM), Candida glabrata ( MIC = 12.5-25 microM), Candida tropicalis ( MIC = 3.15-6.25 microM), Cryptococcus neoformans ( MIC = 0.8-1.6 microM), Saccharomyces cerevisiae ( MIC = 1.6-3.15 microM)]; Refer PubMed ID 28741926: E. coli ATCC 25922 (MIC = 4 microM), S. aureus ATCC 25923 (MIC = 32 microM) , E. coli CGSC 5167 (MIC = 32 microM), K. pneumoniae ATCC 700603 (MIC = 4-8 microM), A. baumannii ATCC 19606 (MIC = 8 microM), P. aeruginosa ATCC 27853 (MIC = 8 microM), H. pylori ATCC 43504 (MIC > 80 microM), C. albicans ATCC 90028 (MIC = 8-16 microM), C. neoformans ATCC 208821 (MIC = 0.5-1 microM)
Hemolytic Activity :
Human erythrocytes (47.2 +/- 6% hemolysis at 64microM)
Validated : Experimentally validated
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in other organism IEA
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0050832 Biological process Defense response to fungus IEA
GO:0044179 Biological process Hemolysis in another organism IEA
Length : 18
Sequence:
ZCRRLCYKQRCVTYCRGR

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