CAMPSQ140
Title : Dermaseptin-B4
GenInfo Identifier : 13959343
Source : Phyllomedusa bicolor [Two-colored leaf frog]
Taxonomy : Animalia, Amphibia
UniProt: P81486
PubMed : 9614066
Activity : Antibacterial
Gram Nature : Gram +ve, Gram -ve
Target :
S. aureus ATCC 25923 ( MIC = 3.0 microM ), P. aeruginosa CIP A22 ( MIC = 4.6 microM ), P. aeruginosa ATCC 27853 ( MIC = 11.6 microM ), E. coli ATCC 25922 ( MIC = 5.0 microM ), E. coli 54127 ( MIC = 2.3 microM )
Validated : Experimentally validated
Pfam : PF12121 : DD_K ( Dermaseptin )
PF03032 : FSAP_sig_propep ( Brevenin/esculentin/gaegurin/rugosin family )
InterPro : IPR004275 : Brevinin.
IPR022731 : Dermaseptin.
IPR020194 : Dermaseptin_anura.
AMP Family : Dermaseptin
Signature :
ID Type Pattern / HMM
DermaseptinH28_12 HMM
DermaseptinH_57 HMM
DermaseptinP28_12 Pattern W-x(3,4)-K-x-[IV]-[GL]-x(2)-A-[AG]-x-A-[AV]-[GL]-x(2)-[AV]-x-[DGTV]-x-[ALV]-[GN]-[AEQ]
Gene Ontology :
GO ID Ontology Definition
Evidence
GO:0005576 Cellular component Extracellular region IEA
GO:0042742 Biological process Defense response to bacterium IEA
GO:0045087 Biological process Innate immune response IEA
Length : 28
Sequence:
ALWKDILKNVGKAAGKAVLNTVTDMVNQ

| © 2022, Biomedical Informatics Centre, ICMR-NIRRCH |
ICMR-National Institute for Research in Reproductive and Child Health, Jehangir Merwanji Street, Parel, Mumbai-400012
Maharashtra, India